Protocol Reference — TB-500

Loading Phase

4-6 weeks

Higher dose to establish tissue saturation

Maintenance Phase

Ongoing (with cycling)

Reduced dose to sustain repair signaling

Off-Cycle

4 weeks minimum

Required rest to prevent receptor desensitization and evaluate baseline healing

Loading Frequency

2-3 injections per week

Split total weekly dose across multiple administrations

Maintenance Frequency

1 injection per week

Single weekly dose sufficient for maintenance signaling