Scheduling, administration, biomarkers, and practical guidance.
Cycle for 12–16 weeks, then 4-week washout
16–24 week cycles; monitor fasting glucose throughout
12-week cycles with 4-week off periods
4–6 week blocks then equal rest period; keep glucose monitor nearby
4–8 week cycles
Transition to maintenance after loading phase
Run continuously as IGF-1 co-factors
Aligns GH pulse with natural nocturnal peak; fasted state prevents blunting by food-induced insulin
Amplifies natural sleep-onset GH surge
Supports VEGF-driven tissue repair during active daytime circulation
Second dose leverages overnight regenerative window
Synergistic GH release timed to nocturnal secretion; food blunts GHRH response
Capitalize on post-exercise nutrient partitioning and insulin sensitivity window