Posts tagged "selank"

Neuroprotection

The peptide revolution promises to rewire your brain — but your immune system might have other plans.

An evidence-based exploration of neuroprotective peptides including GLP-1 receptor agonists, Selank, and Dihexa. We examine clinical promise alongside immunogenicity risks, grey-market purity concerns, and the thin line between neuroregeneration and oncogenic overstimulation.

neuroprotectionpeptidesglp-1selankdihexa+5

Cognitive HealthOutcome

Memory Management

From Dihexa's synaptogenic hammer to Cerebrolysin's clinical track record — five realities of the peptide cognition frontier, and the regulatory minefield around them.

An evidence-based exploration of memory-management peptides including Dihexa, Semax, Selank, P21, and Cerebrolysin. We examine synaptogenic potency claims alongside oncogenic risk, the FDA's 2024 compounding ban, and where clinical evidence ends and biohacking speculation begins.

memory-management

Cognitive HealthOutcome

Focus / ADHD

A clear-eyed map of the peptides and nutritional adjuncts being used for attention and executive function — what the literature supports, what the FDA has banned, and where the biohacking consensus is running ahead of the data.

An evidence-based exploration of focus and ADHD peptides including Semax, Selank, Noopept, Cerebrolysin and their nutritional adjuncts — with the regulatory, retraction and translational-gap landscape that the biohacking coverage tends to leave out.

focus-adhd

Cognitive HealthOutcome

Anxiety / Stress

An evidence-based map of synthetic glyprolines — Selank, Semax, NPY and Pinealon — peptides engineered to modulate the HPA axis and amygdala reactivity without the sedation, dependence or cognitive blunting of benzodiazepines.

A rigorous look at the neuropeptide approach to modern stress: the Pro-Gly-Pro stability trick, the GABAergic-but-not-sedative mechanism of Selank, Semax's ACTH-derived neuroprotection, the Russian clinical evidence base, and the FDA Category 2 constraint that defines legal reality in the US.

anxiety

Immune HealthOutcome

Immune Regulation

The best immune peptides aren't the ones that turn the system up. They're the ones that teach it when to hold still.

Immune regulation is about homeostasis, not amplification. Thymosin Alpha-1 acts as a thermostat — pushing Th1 when the system is under-responsive, pushing T-regs when it's over-firing. Bioregulators work upstream at the level of gene expression. Thymosin Beta-4 regenerates across organ systems. Selank bridges the brain-immune axis. Understanding when to use each — and when not to — is the difference between peptide therapy and peptide tourism.

immune-health

PeptidesPeptide

Selank

A tuftsin-derived heptapeptide that delivers benzodiazepine-level anxiety relief without sedation, dependence, or cognitive fog — while simultaneously boosting immune defence.

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) engineered from the immune peptide tuftsin. It allosterically modulates GABA-A receptors, stabilises endogenous enkephalins, and upregulates BDNF — delivering anxiolysis, cognitive enhancement, and immunomodulation in a single molecule.

selank

SupplementsCompanion

Selank Supplements

The biochemical cofactors your body needs to support Selank therapy.

Evidence-based supplement companion for Selank — a tuftsin-derived heptapeptide that delivers benzodiazepine-level anxiety relief without sedation, dependence, or cognitive fog — while simultaneously boosting immune defence.

selanksupplements

ResearchArticle

The Glyproline Twins: Why Selank and Semax Were Designed to Work Together

Two sister peptides from the same Cold War lab, one calms the emotional floor, the other raises the cognitive ceiling. The mechanistic case for stacking them is architecturally compelling. The clinical evidence for the combination doesn't exist yet.

Selank and Semax are sister heptapeptides engineered with the same glyproline stability tail but from opposite parent molecules, tuftsin (immune) and ACTH (stress). They converge on BDNF through completely different upstream pathways, covering complementary neurochemical territory. This article examines the mechanistic case for combining them, the cofactors that determine whether either signal lands, and where the evidence stops short.

selank

selank

selank

Protocols

Neuroprotection

Memory Management

Focus / ADHD

Anxiety / Stress

Immune Regulation

Selank

Selank Supplements

The Glyproline Twins: Why Selank and Semax Were Designed to Work Together

Protocols

Neuroprotection

Memory Management

Focus / ADHD

Anxiety / Stress

Immune Regulation

Selank

Selank Supplements

The Glyproline Twins: Why Selank and Semax Were Designed to Work Together