anxiolytic

All articles tagged with “anxiolytic”

Protocols

Selank

A tuftsin-derived heptapeptide that delivers benzodiazepine-level anxiety relief without sedation, dependence, or cognitive fog — while simultaneously boosting immune defence.

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) engineered from the immune peptide tuftsin. It allosterically modulates GABA-A receptors, stabilises endogenous enkephalins, and upregulates BDNF — delivering anxiolysis, cognitive enhancement, and immunomodulation in a single molecule.

selankneuroprotectionanxiolyticnootropictuftsin+5

ResearchArticle

The Glyproline Twins: Why Selank and Semax Were Designed to Work Together

Two sister peptides from the same Cold War lab, one calms the emotional floor, the other raises the cognitive ceiling. The mechanistic case for stacking them is architecturally compelling. The clinical evidence for the combination doesn't exist yet.

Selank and Semax are sister heptapeptides engineered with the same glyproline stability tail but from opposite parent molecules, tuftsin (immune) and ACTH (stress). They converge on BDNF through completely different upstream pathways, covering complementary neurochemical territory. This article examines the mechanistic case for combining them, the cofactors that determine whether either signal lands, and where the evidence stops short.

selank

Protocols

PeptidesPeptide

Selank

A tuftsin-derived heptapeptide that delivers benzodiazepine-level anxiety relief without sedation, dependence, or cognitive fog — while simultaneously boosting immune defence.

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) engineered from the immune peptide tuftsin. It allosterically modulates GABA-A receptors, stabilises endogenous enkephalins, and upregulates BDNF — delivering anxiolysis, cognitive enhancement, and immunomodulation in a single molecule.

selankneuroprotectionanxiolyticnootropictuftsin+5

ResearchArticle

The Glyproline Twins: Why Selank and Semax Were Designed to Work Together

Two sister peptides from the same Cold War lab, one calms the emotional floor, the other raises the cognitive ceiling. The mechanistic case for stacking them is architecturally compelling. The clinical evidence for the combination doesn't exist yet.

Selank and Semax are sister heptapeptides engineered with the same glyproline stability tail but from opposite parent molecules, tuftsin (immune) and ACTH (stress). They converge on BDNF through completely different upstream pathways, covering complementary neurochemical territory. This article examines the mechanistic case for combining them, the cofactors that determine whether either signal lands, and where the evidence stops short.

selank

semax

neuroprotection

bdnf

gaba

+9