Posts tagged "SS-31"

Endurance / Stamina

Mitochondria-derived peptides like SS-31 and MOTS-c are rewriting the rules of cellular energy — but the translational gap between mouse models and human performance remains wide open.

The mitochondrial revolution is moving beyond generic antioxidants toward precision peptides that stabilize the inner membrane and restore fading cellular signals. SS-31 tightens the elastic of the cell while MOTS-c acts as an exercise mimetic encoded in our own DNA — yet clinical reality checks remind us that promising preclinical data does not always survive the journey to the pharmacy.

endurancestaminamitochondriaSS-31elamipretide+7

Cellular HealthOutcome

Mitochondrial Function

Our DNA is not a static blueprint of decline but a dynamic epigenetic landscape that can be re-tuned through precise molecular signaling.

Aging is a profound loss of transcriptional access, not just mechanical wear. Mitochondrial peptides like MOTS-c and SS-31, alongside epigenetic bioregulators such as Epitalon and Livagen, are rewriting the longevity playbook by restoring chromatin architecture and stabilizing the mitochondrial membrane. This protocol maps the frontier from deheterochromatinization to FDA-approved cristae repair.

mitochondrial-function

Cardiovascular HealthOutcome

Cardiovascular Health

Cardiac peptide therapy isn't science fiction — Tβ4 has completed Phase 2 in acute MI (NCT05984134), and SS-31 sits in advanced-phase trials for mitochondrial heart disease.

A plain-English look at the peptides being investigated for cardiovascular repair — Thymosin β4 for post-infarct tissue regeneration, elamipretide for mitochondrial membrane stability, and the adjacent vascular-bioregulator layer.

Thymosin Beta-4

SS-31

SS-31

Protocols

Endurance / Stamina

Mitochondrial Function

Cardiovascular Health

Protocols

Endurance / Stamina

Mitochondrial Function

Cardiovascular Health