ARA-290
An 11-amino-acid peptide derived from erythropoietin's helix-B surface that selectively activates the Innate Repair Receptor, triggering nerve regeneration and tissue protection without the blood-thickening risks of EPO.
ARA-290 isolates the tissue-repair signal from erythropoietin without stimulating red blood cell production. Phase II trials showed a 23% increase in corneal nerve fiber area in sarcoidosis patients, proving structural nerve regeneration rather than symptomatic relief. The molecule also improved HbA1c and lipid profiles in diabetic trials, with effects lasting weeks beyond the final dose.
ARA-290